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An official FDA step is still needed before the legal position changes under the 503A Bulks List pathway

Li Y, Foster W, Deasy BM, Chan Y, Prisk V, Tang Y, Cummins J, Huard J: Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis

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This enzyme achieves this promiscuity primarily through rapid transpersulfidation of C201 in a CstB-unique loop relative to a canonical PDO, followed by molecular shuttling of a covalently bound sulfonate group to a persulfidated C408, and thiosulfate release